ACLS Certification - Official Site | Powered by CPR.com
ACLS Certification - Official Site | Powered by CPR.com Contact Us | 1-800-448-0734 |e-Verify | Log in |

Get BLS Certified Today

The Systematic Approach to the Seriously Ill Patient

ACLS Certification Association videos have been peer-reviewed for medical accuracy by the ACA medical review board.

Article at a Glance

  • When a patient is acutely and seriously ill, it is important to approach in a systematic fashion so nothing is missed.
  • When a patient is unconscious or unresponsive, the mnemonic DRS ABCD (danger, response, shout for help, airway, breathing, circulation, defibrillation) can help in remembering the steps involved in providing basic life support (BLS).
  • When a patient is unconscious, the primary assessment is performed after BLS; for the conscious patient, perform the primary assessment first.
  • The primary assessment includes airway, breathing, circulation, disability, and exposure (ABCDE).
  • Obtaining a focused history is done during the secondary assessment.

Calling 9-1-1, activating the emergency response system.

Calling 9-1-1 activates the emergency response system.

BLS Assessment: Know your DRS ABCD

The following is an outline of the systematic approach to assisting the cardiac arrest patient. The BLS assessment is the foundation of all life support activities in emergency situations where the patient is unconscious. 

The BLS assessment is composed of six steps:

STEP 1: Ensure scene safety (no danger).

STEP 2: Check for a response.

STEP 3: Shout for help and activate the emergency response system.

STEP 4: Check for abnormal breathing or no breathing. Check for a pulse. No pulse and abnormal breathing indicate a cardiac arrest. Retrieve the automated external defibrillator (AED) or the crash cart with a defibrillator (or ask a bystander or colleague to do so).

STEP 5. Begin high-quality cardiopulmonary resuscitation (CPR) (starting with compressions). Apply the AED or defibrillator pads and use it as soon as it is ready.

STEP 6. As soon as an additional rescuer arrives, provide two-person CPR. Utilize the AED or defibrillator.

DRS ABCD mnemonic for BLS assessment.

DRS ABCD Mnemonic

These six easy steps can be remembered by the mnemonic: DRS ABCD (danger, response, shout for help, airway, breathing, circulation, and defibrillation).


Read: Bradycardia with a Pulse Algorithm Explained


he systematic approach.

The Systematic Approach

Primary Assessment

For the conscious patient, the provider should perform the primary assessment: know the ABCDE mnemonic. For the unconscious patient, the primary assessment is performed after the BLS assessment.1


Related Video – Understanding the Steps of the Primary Assessment


If the patient is conscious or has regained consciousness after performing high-quality CPR, then the advanced cardiovascular life support (ACLS) provider performs the primary assessment, which comprises the ABCDE mnemonic.

A = airway: Maintain airway patency, especially in the unconscious patient. 

Use maneuvers such as the head tilt-chin lift or jaw-thrust.2 Use an airway, such as an oropharyngeal airway, for unconscious patients or a nasopharyngeal airway for conscious or semiconscious patients with an active gag reflex. Insert an advanced airway (endotracheal tube, laryngeal mask, laryngeal tube, or an esophageal-tracheal tube) as soon as possible if hypoxic arrest is suspected.

B = breathing: Give supplementary oxygen — 100% for cardiac arrest patients or titrate to achieve 94% or higher for others. Avoid excessive ventilation.3 Monitor for adequate ventilations (chest rise, capnography, O2 saturation, and auscultation).

C = circulation: Monitor CPR quality: capnography (partial pressure of end tidal CO2 [PETCO2]) must be > 10 mm Hg and intra-arterial pressure must be > 20 mm Hg. If these parameters are low, improve CPR quality. Monitor cardiac rhythm with a cardiac monitor or defibrillator. Provide shocks as indicated, depending on rhythm. Obtain intravenous (IV) or intraosseous (IO) access and give fluids as necessary.

D = disability: Check neurologic function (Glasgow Coma Scale [GCS], neurologic examination) and observe pupillary dilatation and level of consciousness using the AVPU mnemonic: alert, verbal, pupils, and unresponsive. Check glucose, temperature, and perfusion issues.

E = exposure: Perform a quick physical examination to look for obvious reasons for cardiac arrest, such as trauma, burns, hemorrhaging, and other unusual findings. Some patients may be wearing medical bracelets. It may be necessary to remove some of the patient’s clothing. Keep the patient warm and remember to examine the patient’s posterior surfaces as well.

ABCDE mnemonic for the primary assessment.

The ABCDE mnemonic is a way to help memorize the primary assessment.

Secondary Assessment

The secondary assessment includes obtaining a focused medical history to identify potential causes of cardiac arrest. After identifying the cause, the provider performs necessary interventions. To rule out possible diagnoses, use the mnemonic SAMPLE: signs and symptoms, allergies, medications, past medical history, last meal consumed, and events that led up to the present illness.


Related Video – Understanding the Secondary Assessment Steps


The Hs and Ts mnemonic is part of the secondary assessment.

Hs include hypovolemia, hypoxia, hydrogen ion (acidosis), hypo- or hyperkalemia, and hypothermia. 

Ts include tension pneumothorax, tamponade, toxins, and thrombosis (pulmonary and coronary). 

The Hs and Ts mnemonic is an invaluable tool to help determine the possible causes of cardiac arrest.


Related Video – One Quick Question: What are Hs and Ts?


The mnemonics presented in this article help the healthcare provider care for the acutely or seriously ill patient in a systematic approach.

More Free Resources to Keep You at Your Best

ACLS Certification Association (ACA) uses only high-quality medical resources and peer-reviewed studies to support the facts within our articles. Explore our editorial process to learn how our content reflects clinical accuracy and the latest best practices in medicine. As an ACA Authorized Training Center, all content is reviewed for medical accuracy by the ACA Medical Review Board.


1. American Heart Association. Advanced Cardiovascular Life Support. 2000.

2. Queen’s University School of Medicine. Simple Airway Maneuvers.

3. United States National Library of Medicine. Reduction of Oxygen After Cardiac Arrest. 2020.

More to Learn

By Justin Poole, MD | Medically reviewed by Jennifer Bunn, RN

ACS and STEMI Systems of Care

ST-elevated myocardial infarction (STEMI), the most common cause of cardiac arrest in adults, has a well-organized "system of care". Learn the steps and protocols in our detailed article.

By Eileen Johnson, RN | Medically reviewed by Jennifer Bunn, RN

AHA Guidelines Update: 2017

Keep your life-saving skills current with the 2017 AHA focused update on adult and pediatric basic life support and CPR. Included are the revised AHA guidelines regarding cardiopulmonary resuscitation and ECC.