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What is the Clotting Cascade? – Video

ACLS Certification Association videos have been peer-reviewed for medical accuracy by the ACA medical review board.

Video at a Glance

  • Clotting cascade refers to the series of enzymes activated in the formulation of a blood clot.
  • Platelets and proteins work together to form a clot.
  • PT measures how fast a patient’s blood can clot when mixed with tissue factor.
  • There are multiple pathways for clot-making.
  • PTT measures how fast a patient’s blood can clot when not mixed with tissue factor.
  • All clotting pathways converge at factor 10.

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