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Pathophysiology of Hemolytic Disease of the Newborn Video
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Video at a Glance
- This video discusses the pathophysiology of hemolytic disease of the newborn.
- If an Rh-negative mother and an Rh-positive father have a baby, the baby has a 50% chance of being Rh-positive.
- During birth, the mother’s placenta blood barrier breaks down, and some of the baby’s blood gets into the mother’s bloodstream, exposing her to Rh-positive blood.
- Over the coming weeks, the mother will begin to have an antigenic response to the new blood.
- In another situation, the mother and father’s next baby is Rh-negative, and the mother’s antibody-generating plasma cells enter the baby’s bloodstream during birth. Hours later, the baby presents with hemolysis.
- The treatment is to administer the mother anti-Rh Rhogan medication.
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