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Anatomy of the Gastrointestinal Tract Video

ACLS Certification Association videos have been peer-reviewed for medical accuracy by the ACA medical review board.

Video at a Glance

  • The GI tract is composed of several layers.
  • The innermost layer is the lumen, followed by the mucosa, the muscularis, and the serosa or mesentery layer.
  • Peyer’s patches located in the lumen are lymph nodes lined with T lymphocytes and M cells which are responsible for immune surveillance and response.
  • The layer between the muscularis and the mucosa is called the submucosa and is filled with blood vessels and submucosal glands which produce mucus.
  • Most of the GI tract contains two muscle layers, longitudinal and circular, while the stomach has an extra layer, the oblique muscles that are responsible for churning.
  • The gut has two layers of nerves called the enteric nervous system.
  • The first layer is the myenteric plexus that controls the gut’s smooth muscles and directs peristalsis, while the second layer is the submucosal plexus, which controls secretions.

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